In Django, you can use either ViewSets or APIViews to create APIs for your web application. Here are some factors to consider when choosing between ViewSets and APIViews:

1. Complexity: If you need to implement a simple API that only requires basic CRUD (Create, Read, Update, Delete) operations on a single model, then ViewSets would be a good choice. However, if you need to implement a more complex API that requires custom logic or interactions with multiple models, then APIViews would be a better choice.

2. Flexibility: ViewSets are generally more flexible and require less code to implement basic functionality. However, they may not be suitable for more complex use cases. APIViews, on the other hand, provide more flexibility and control over the behavior of your API.

3. Customization: APIViews provide more customization options than ViewSets. With APIViews, you can define your own methods and handle custom behavior for each method. With ViewSets, you are limited to the default CRUD operations.

4. Authentication and permission: APIViews provide more advanced authentication and permission handling options than ViewSets. With APIViews, you can easily implement custom authentication and permission classes to control access to your API.

In general, if you need to implement a simple API that only requires basic CRUD operations, then ViewSets would be a good choice. However, if you need more flexibility and control over the behavior of your API, or need to implement more complex logic or interactions with multiple models, then APIViews would be a better choice. Additionally, if you need advanced authentication and permission handling options, then APIViews would be the way to go.